Venice. 1704. In this city of glittering splendour, desperation and destitution are never far away. At the Ospedale della Pietà, abandoned orphan girls are posted every day through a tiny gap in the wall. Anna Maria is just one of the three hundred girls growing up within the Pietà's walls - but she already knows she is different. Obsessive and gifted, she is on a mission to become Venice's greatest violinist and composer, and in her remarkable world of colour and sound, it seems like nothing will stop her. But the odds are stacked against an orphan girl - so when the maestro selects her as his star pupil, Anna Maria knows she must do everything in her power to please this difficult, brilliant man. But as Anna Maria's star rises, threatening to eclipse that of her mentor, the dream she has so single-mindedly pursued is thrown into peril.